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UDK 616-053.2 CODEN PCROE6 ISSN 1330-724X   Vol. 46 Suppl 1 2002
PAEDIATRIA CROATICA
Paediatr Croat  Vol. 46 travanj 2002.

THE FIRST EXPERIENCES WITH BOTULINUM TOXIN TYPE A IN CHILDREN WITH CEREBRAL PALSY

A. Sasso, J. Zec-Mikuličić, A. Stošić, I. Bajok

The results of use of Botulinim-A toxin (Botox, Allergan) in 16 children (the mean age: 4,3 years) with cerebral palsy. The dose of 3-5 units/kg was injected. The mesuring of outcome during 4-11 months included clinical assessment based on opinion of physicians, parents, physical terapeuts, functional evaluating of gait (PRS), muscle tone grading (modified Aschworth scale) and measuring the range of motion. The results were statisticaly significant, lasting 3-7 months, included decreased spasticity, improvments of gait and facilitating physical therapy. The aplication was then repeated. The undiserable side efects or complications were not observed.